Brainwaves by Burak Büyükdemir
Field notes from 26 years of investing in early-stage startups.
June 23, 2026
6 Startups I Met in May & June
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I talk to founders every day, and every one of them teaches me something new. As an early-stage investor, I meet extraordinary people building bold products.
This time the pattern surprised me. While most of my inbox is AI wrappers, the founders who stuck with me in May and June were all building hard, physical things — space computers, synthetic blood, even snow grown from protein. None are in my portfolio yet. I'm just sharing the ones I can't stop thinking about.
If you'd like to invest alongside me, you can join here — I'm always happy to share my deal flow. And if you're a founder raising capital, feel free to email me your pitch deck. I take a look at every one, and if it makes sense, we'll jump on a call.
Here are the 6 startups I met in May and June — what do you think?
The Startups I Met
1️⃣ Novo Space — USA 🇺🇸
Radiation-tolerant, modular space computers — plug-and-play boards that claim to cut satellite development ~100x. Already flew on a NASA Moon mission; customers include Maxar, AST SpaceMobile, and the US Air Force. Now raising a Series A.
🔗 novo.space
2️⃣ Inflection Space — USA 🇺🇸
Satellite buses built ~90% in-house from qualified off-the-shelf parts, targeting a $250K bill of materials vs. $4M+. Founded by ex–Rocket Lab engineers.
🔗 inflection-space.com
3️⃣ Foundational Bio — USA 🇺🇸
A fully automated, AI-run wet lab. First service: whole-genome sequencing at ~$150 a sample.
🔗 foundational.bio
4️⃣ Odola — USA 🇺🇸
Protein-engineered, hemoglobin-based synthetic blood — built to replace our donor-dependent transfusion supply.
🔗 odolalabs.com
5️⃣ Supercool Earth — USA 🇺🇸
Protein-based snowmaking and cloud seeding — a biological alternative to silver iodide. First fermentation run done; targeting ski-resort revenue this winter.
🔗 supercool-earth.com
6️⃣ SpaceTime Industries — USA 🇺🇸
Autonomous software that defends subsea cables, fusing radar and AIS to detect threats and dispatch a response. A ~$1.8M contract is already in discussion.
🔗 submarinecablesecurity.com
Every one of these founders brings a bold story, a sharp sense of purpose, and a real solution to a real problem. The common thread: they're not building demos — they're building things that are genuinely hard to build, and that difficulty is the moat.
Which one would you back? Hit reply or vote below.
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